The COVID-19 pandemic in Nepal is part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first case in Nepal was confirmed on 23 January 2020 when a 31-year-old student, who had returned to Kathmandu from Wuhan on 9 January, tested positive for the disease. It was also the first recorded case of COVID-19 in South Asia. Nepal's first case of local transmission was confirmed on 4 April in Kailali District. The first death occurred on 14 May. A country-wide lockdown came into effect on 24 March 2020, and ended on 21 July 2020
Between January and March, Nepal took steps to prevent a widespread outbreak of the disease while preparing for it by procuring essential supplies, equipment and medicine, upgrading health infrastructure, training medical personnel, and spreading public awareness. Starting in mid-January, Nepal established health-desks at Tribhuvan International Airport as well as on border checkpoints with India. Land borders with India as well as China were later completely sealed off, and all international flights were suspended. All academic examinations were cancelled, and schools and colleges were closed. Quarantine centers and temporary hospitals are being set up across the country.
The vaccination for COVID-19 began from the 27th January, 2021.